BBI Solutions increases capacity for transferrin production


BBI Solutions (BBI) has invested in its facilities and resources to increase the capacity of cell culture native human transferrin production by up to 40%

BBI has manufactured transferrin for over 10 years

Human transferrin is a natural and often essential component to promote cell growth in many cell culture applications and it is frequently used in serum free media, where it acts as an iron transporter.

Stephane Argivier, BBI’s Director of Product Management, said: “Demand for our cell culture grade transferrin was growing at such a rate that we had reached our full capacity. In response to market demand we saw the opportunity to increase our capacity to meet the needs of our customers and provide room for growth.”

BBI has been manufacturing human holo, apo and sidero grades of transferrin for more than 10 years.

In this time growth in the cell culture market has been noticeable and it is predicted that it will continue to grow. Forecasts predict it will be worth US$18.63 Billion by 2020 (CAGR 10.5%).1

Factors triggering growth include: increasing incidence of chronic diseases; increasing regulatory approvals for cell culture based vaccines; funding for cell-based research and technological advancements in cell culture products.1

BBI’s production capacity has seen substantial improvements to the manufacturing facilities at its site in Sittingbourne, England.

Investing £150000 in new machinery and increasing resource capabilities.

BBI’s human transferrin is manufactured under the ISO 13485 quality management system. BBI provide high specification material at a large scale and have excellent batch-to-batch consistency.

The human transferrin is pasteurised and filtered at 0.2µm to guarantee low mycoplasma and low bioburden.

BBI can also control many other parameters, such as moisture and iron levels, to meet customer’s specifications and requirements.

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1. Markets and Markets,"Cell Culture Market by Equipment, Consumables, Application, End Users: Forecast to 2020"