Thermo Fisher introduces online 2D-LC chromatography system

Automating workflows is designed to accelerate sample analysis time, maximise sample integrity, and improve confidence in the results

Thermo Scientific Vanquish Online 2D-Liquid Chromatography (LC) Systems offers a platform for pharmaceutical/biopharmaceutical R&D, food safety, environmental testing, omics and polymer analysis scientists to characterise samples.

The system uses the company’s Vanquish technology, while offering flexibility and versatility for multi-dimensional liquid chromatography. The platform delivers peak identification and purity analysis for difficult to separate analytes, for example, structural isomers. The system is suitable for laboratories in fields such as pharmaceutical/biopharmaceutical R&D, food safety, environmental testing, omics and polymer analysis, combining the confidence of 2D-LC and productivity boost of Dual LC in one system, while not requiring dedicated 2D-LC instrumentation.

Integrating the online 2D-LC system with complimentary LC assays enables improved sample throughput while increasing confidence in results, Thermo Fisher says. Key applications include making legacy methods with UV detection and non-volatile buffer usage compatible with mass spectrometry (MS) detection. Automating workflows is designed to accelerate sample analysis time, maximise sample integrity, and improve confidence in the results.

"Confident, accurate and robust analysis is essential for difficult to resolve analytes in complex samples, such as biopharmaceutical formulations, fermentation broths or polymer materials," said Frank Steiner, Senior Manager, Product Applications and Scientific Advisor, High Performance Liquid Chromatography, Thermo Fisher Scientific. "The Vanquish Online 2D-LC system offers full peak characterization, with complete, automated and flexible workflows, allowing customers to expand their analytical capabilities while presenting a user-friendly experience."

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Thermo Fisher Scientific (more information, website)