Shimadzu enhances dual ion source technology with compact LCMS-2050

Published: 23-Sep-2025

The system combines high-speed analysis, energy efficiency, and advanced DUIS capability in a compact design

Shimadzu’s LCMS-2050 Liquid Chromatograph Single Quadrupole Mass Spectrometer showcases an impressive heated dual ion source (DUIS) capability, combining electrospray (ESI) and atmospheric pressure chemical ionisation (APCI) simultaneously in a compact form factor. This advanced design maintains a full-length quadrupole to support high-speed, high-sensitivity analysis while maintaining superior detection performance for a diverse range of samples. The heated DUIS, equipped with both an ESI spray nozzle and an APCI corona needle, enables the simultaneous detection of high-polarity molecules like Simetryn and low-polarity molecules like Quintozene, which are challenging to detect using ESI alone.

The incorporation of ultrafast technology, including a 15,000 u/sec scan speed and a 10 msec polarity switching time, ensures that high data quality is preserved even with unknown or complex samples with the narrowest of peaks. The LCMS-2050’s space-saving design allows it to fit neatly into the same space as a standard LC component and achieves 43% energy savings compared to previous models.

Utilising Shimadzu's LabSolutions LCMS software, the system simplifies data review by displaying LC/MS chromatograms and UV/MS spectra in a single window, with the capability to annotate mass information directly onto the UV chromatogram, making it suitable for all users.

The LCMS-2050, with its compact size and advanced DUIS technology, represents a significant leap forward in mass spectrometry, providing a powerful, efficient, and space-saving solution for high-performance liquid chromatography.

Trending Articles

Relevant companies

You may also like