Manufacturing Chemist

How self-replicating RNA can transform in vitro-transcribed drug development

In vitro-transcribed (IVT) ribonucleic acids (RNAs) are integral to next-generation nucleic acid-based drugs. The recent success of messenger RNA (mRNA)-based vaccines against COVID-19 created new opportunities to untangle their working mechanism, advantages and disadvantages. Kerstin Pohl, Senior Manager, Cell & Gene Therapy and Nucleic Acids, SCIEX, reports

Farmabios achieves cGMP approval for large-scale HPAPI and steroid production

Axplora company Farabios has announced the cGMP approval from the national public body regulating medicines for human use in Italy (AIFA) for the first line of its new production unit

Multiply Labs' robotic pharmaceutical manufacturing project reaches proof-of-concept

The consortium which contains Multiply Labs, Thermo Fisher, Cytiva, UCSF and Charles River has reached proof-of-concept on a robotic and automated cell manufacturing system

Poolbeg Pharma to use unique oral delivery platform for new condition

A strategic collaboration has been agreed with a biopharma to focus on the development of an optimised drug for a metabolic condition using Poolbeg’s licensed oral delivery technology

Clariant launches new range of excipients to improve stability and solubility of APIs

Clariant Health Care has expanded its range of functional excipients to solve active pharmaceutical ingredient (API) delivery & bioavailability challenges

Automation expert Hamilton expands to forge partnerships in pharma and life sciences

The expert in automation technology and analytical sensors has announced a significant expansion and enhancement of its Field Services division

EnginZyme produces key mRNA vaccine ingredient pseudouridine using biocatalysis

The Sweden-based deep-tech company whose cell-free biomanufacturing technology uses the power of enzymes to create sustainable products and processes for a variety of industries, has announced that it has patented a process to synthesise pseudouridine

Itema and Tofflon launch Tofflonit to serve European biopharma sector

Italy-based Itema and China-based Tofflon Science And Technology Group have launched the new joint venture for the production of industrial lyophilisers for the biopharmaceutical sector

Breaking News

MIMETAS and Yamaha Motor Sign Joint Marketing Agreement Aimed at Advancing Therapeutic Development

MIMETAS and Yamaha Motor Sign Joint Marketing Agreement Aimed at Advancing Therapeutic Development

Both companies will collaborate to develop innovative applications of the CELL HANDLER in combination with MIMETAS’ 3D tissue models

Calliditas’ partner Everest Medicines announces China NMPA’s approval of Nefecon

Calliditas’ partner Everest Medicines announces China NMPA’s approval of Nefecon

China's National Medical Products Administration (NMPA) has approved Nefecon for the treatment of primary immunoglobulin A nephropathy (IgAN) in ad...

CN Bio wins "Most Impactful Industry Collaboration of the Year" at the OBN Awards

CN Bio wins "Most Impactful Industry Collaboration of the Year" at the OBN Awards

Six-year collaboration recognised at prestigious awards ceremony for its continued success in advancing OOC research to support widespread adoption...

The roadmap to success in the cannabinoid drug development journey

The roadmap to success in the cannabinoid drug development journey

The key to success in the development and registration of cannabinoid-based medicines hinges on choosing a GMP-certified high-purity active ingredi...

New capital strengthens ProtaGene's advanced analytical leadership in the biologics and CGT markets

New capital strengthens ProtaGene's advanced analytical leadership in the biologics and CGT markets

ProtaGene GmbH, a leading global contract research organization (CRO) dedicated to advanced analytics for biologics and cell and gene therapies, an...

CatSci expands capabilities to offer expert cGMP analytical development services

CatSci expands capabilities to offer expert cGMP analytical development services

CatSci is thrilled to announce the launch of its expert cGMP analytical capabilities in Dagenham, UK

Diagnosing hormone-based disorders using saliva

Diagnosing hormone-based disorders using saliva

Diagnosing hormone-based disorders using saliva samples dates back to the 1980s; however, it’s only the sensitivity improvements that have occurred...

How to proactively address EU HTAR implementation challenges before 2025

How to proactively address EU HTAR implementation challenges before 2025

Data landscape challenges within the European Union (EU) have historically been driven by the different laws, processes and regulatory standards of...

Symbiosis Pharmaceutical Services granted MHRA licence following a £1m investment

Symbiosis Pharmaceutical Services granted MHRA licence following a £1m investment

Symbiosis Pharmaceutical Services, has launched new in-house analytical and microbiological capabilities to enable testing of small molecule, biolo...

Xybion acquires Autoscribe Informatics to expand its LIMS business

Xybion acquires Autoscribe Informatics to expand its LIMS business

Xybion Corporation is pleased to announce the acquisition of Autoscribe Informatics. This represents a significant strategic expansion in the compa...

The right validation model: practical considerations and applications

The right validation model: practical considerations and applications

It is widely accepted that validation in the life sciences industry follows a lifecycle model (1,2). What is not always clear is the specific model...

Adding more to the cell and gene therapy playbook

Adding more to the cell and gene therapy playbook

With notable advances in various forms of administration, including making the use of viral vectors safer, non-viral delivery with lipid nanopartic...

More than 3000 cacti send a clear message for sustainable lab practices

More than 3000 cacti send a clear message for sustainable lab practices

More than 3000 cacti have been planted in Starlab TipOne racks as a daily reminder to laboratory scientists to put sustainability at the core of th...

Analytical method development in a high potent facility

Analytical method development in a high potent facility

Analytical method development is a cornerstone of pharmaceutical outsourcing. In this Q&A with Dr Kevin Robinson (KSR), Amanda Blackwell (AB), Head...

TÜV Rheinland is now a UK approved body according to UK MDR

TÜV Rheinland is now a UK approved body according to UK MDR

TÜV Rheinland has been designated by the UK competent authority “Medicines and Healthcare products Regulatory Agency” to do UKCA certification in a...

Investing in a manufacturing infrastructure to harness tumour-infiltrating lymphocytes (TILs) for cancer treatment

Investing in a manufacturing infrastructure to harness tumour-infiltrating lymphocytes (TILs) for cancer treatment

In this article, Dr Chantale Bernatchez, Director of Process Development at CTMC, highlights the need for a standardised TIL manufacturing process...

In Brief

Asynt confirm expansion of novel photochemistry range

Turning up the heat with SF-10+

‘Next generation’ capsule filling machine showcased by ACG

Enteric delivery of my API: how to make it right?

Schreiner MediPharm Enables Digital Adherence Monitoring with New Child-Resistant Smart Blister Wallet

Anton Paar launches the Multiwave 7101/7301/7501 Series

Nordic-Irish Process Chemistry Forum 2023

New Vink Chemicals production site

Tri-coded storage tube optimised for maximum sample recovery

Vitafoods Europe

Future-proof cooling: Why pre-insulated plastic piping systems improve the sustainability of HVAC applications

Calibre Scientific acquires Scientific Support Services

Electrolux Professional unveils new series of high capacity barrier washers for hygiene-critical applications

Therapeutic: nemolizumab for prurigo nodularis

A bronze beginning with infinite possibilities

Pharma posts end-of-year bounce as CPHI Barcelona reports record attendance

Compliance software and IQ/OQ/PQ services for particle sizing

New Emerson high-flow solenoid valve increases plant reliability and operating efficiency

C2 PHARMA receives DMF approval in China for pilocarpine nitrate

Epro achieves ISO 9001 certification

Tower Cold Chain and Cardiff Business School study reveals the key to enhancing operational efficiency

New LIMS functionality showcased at Lab Innovations 2023

Most Popular

Inspiration and Learning

Manufacturing Chemist Stand Side with ACG

Manufacturing Chemist Stand Side with ACG

Manufacturing Chemist Stand Side with Lonza

Manufacturing Chemist Stand Side with Lonza

Manufacturing Chemist Stand Side with Piramal Pharma Solutions

Manufacturing Chemist Stand Side with Piramal Pharma Solutions

Manufacturing Chemist Stand Side with Syntegon

Manufacturing Chemist Stand Side with Syntegon

Manufacturing Chemist Stand Side with C2 Pharma

Manufacturing Chemist Stand Side with C2 Pharma

Manufacturing Chemist Stand Side with Almac

Manufacturing Chemist Stand Side with Almac

Enteric delivery of my API: how to make it right?

Enteric delivery of my API: how to make it right?

Find the right diaphragm valve for pharmaceutical applications - DOWNLOAD THE NEW REPORT

Find the right diaphragm valve for pharmaceutical applications - DOWNLOAD THE NEW REPORT

Cleaning validation and verification in a high potent granulation suite

Cleaning validation and verification in a high potent granulation suite

Manufacturing Chemist in conversation with Cytiva

Manufacturing Chemist in conversation with Cytiva

Careers

Broken String Biosciences appoints Gavin Burns as Vice President of Quality and Operations

Change of management at the Romaco facility in Karlsruhe

Aptar Digital Health expands oncology clinical advisory board

Cherwell welcomes new recruits as pharma environmental monitoring needs grow

New expert advisory board appointments set to drive growth and innovation at Hongene

Myricx Bio appoints Dr Chris Martin as Chair of its Board of Directors

Axplora announces the appointment of its Scientific Advisory Board

Christian Praxmarer becomes new CEO of Single Use Support

Management changes at EyeC: Markus Fietkau is the new Sales Director

SENISCA strengthens board with the appointment of Dr David Chiswell as Chair

Reports

The roadmap to success in the cannabinoid drug development journey

The roadmap to success in the cannabinoid drug development journey

Diagnosing hormone-based disorders using saliva

Diagnosing hormone-based disorders using saliva

The right validation model: practical considerations and applications

The right validation model: practical considerations and applications

Analytical method development in a high potent facility

Analytical method development in a high potent facility

Investing in a manufacturing infrastructure to harness tumour-infiltrating lymphocytes (TILs) for cancer treatment

Investing in a manufacturing infrastructure to harness tumour-infiltrating lymphocytes (TILs) for cancer treatment

Simplifying technology transfer to get drugs to market faster

Simplifying technology transfer to get drugs to market faster

Bio-Courier: a new delivery technology to increase the global accessibility of RNA therapeutics

Bio-Courier: a new delivery technology to increase the global accessibility of RNA therapeutics

What’s in a partner? The essential facets of a strong biopharma collaboration

What’s in a partner? The essential facets of a strong biopharma collaboration

How self-replicating RNA can transform in vitro-transcribed drug development

How self-replicating RNA can transform in vitro-transcribed drug development

Overcoming cell separation challenges to advance stem cell therapy research

Overcoming cell separation challenges to advance stem cell therapy research