Latest in Research & Development

New small molecule shows promise in stopping lung cancer growth

Researchers have identified AVJ16, a drug candidate that blocks the cancer-driving protein IGF2BP1, halting tumour growth in preclinical models whilst sparing healthy cells

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From box to bedside: unlocking patient-centric care with connected packaging

Pharmaceutical packaging is playing an increasing role in patient–centric care. The integration of smart 2D codes and connected digital platforms can provide a direct link...
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Quantoom Biosciences partners with Memorial Sloan Kettering Cancer Center to advance personalised mRNA cancer therapeutics

Quantoom Biosciences will use MSK's proprietary lipid nanoparticle technology, Ncapsulate QCX-002, in the development of personalised RNA-based cancer therapies, with plans to support upcoming Phase I clinical trials

AbbVie submits new drug application to FDA for tavapadon in Parkinson’s disease treatment

The once-daily oral dopamine D1/D5 receptor partial agonist has been supported by positive Phase III TEMPO trial results that show symptomatic improvement across the Parkinson’s disease spectrum
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Formulation meets function: addressing palatability in drug development (part II)

Part I of this article examined the critical role of palatability in patient adherence to treatment regimens, the underlying biological challenges of bitterness in medications and the innovative strategies used to create more acceptable and effective drug formulations

AI-powered Viro3D becomes world’s largest database of human and animal virus proteins

Scientists at the MRC-University of Glasgow Centre for Virus Research have launched a free database containing structural models for 85,000 proteins from 4400 viruses, paving the way for faster development of vaccines and antiviral drugs

Prellis biologics partners with Eli Lilly to advance next-generation human antibody therapeutics

Prellis will combine its EXIS organoid and AntiGen AI platforms with Lilly’s research and development expertise, aiming to accelerate the discovery of fully human antibodies for multiple disease targets

Concept Life Sciences opens expanded drug discovery facilities in Chapel-en-le-Frith

The expansion makes the facility one of the UK’s largest integrated drug discovery sites, bringing chemistry, ADMET and screening biology under one roof

Pi Health partners with GSK to accelerate global oncology clinical trial

Physician-led Pi Health will deploy its AI-powered FICS platform and end-to-end clinical research services to manage a Phase II oncology study for GSK, aiming to cut trial timelines by up to 50% while enhancing data quality and regulatory readiness

Continuous innovation: redefining the future of pharmaceutical manufacturing

In an industry in which reliability is paramount and change can be slow, GEA has consistently proven that innovation and stability go hand in hand. Almost two decades ago, GEA introduced the first ConsiGma® continuous manufacturing (CM) system to the pharmaceutical market — a pioneering move that helped to reshape how oral solid dosage (OSD) forms are developed and produced

Latest posts in Research & Development

Huntington's breakthrough: gene therapy appears to slow progression of disease by 75%

uniQure has announced positive topline results from a Phase I/II clinical trial of a new Huntington's disease treatment, spurring hopes that more people at risk will undergo testing

Australian scientists develop next-generation lipid nanoparticles to transform drug delivery and mRNA therapeutics

The lipid nanoparticles (LNPs) form cube and hexagon arrangements and could advance cancer treatments, gene therapies and diagnostics while offering a more affordable alternative to current LNP platforms

FDA authorises OGT companion diagnostic for acute leukaemia

The emergence of precision therapies, such as the menin inhibitor Revuforj (an oral inhibitor of the menin–KMT2A interaction), offers new avenues to improve outcomes for patients with these challenging acute leukaemia cases

Spiky magnetic nanorobots pierce tumour defences to boost chemotherapy

In lab and animal studies, the “microscopic scalpels” enhanced drug delivery, reduced tumour growth and extended survival, offering a potential new weapon against drug-resistant cancers

CHMP recommends Sanofi and Regeneron’s Dupixent to treat chronic spontaneous urticaria in EU

If approved, it would be the first targeted CSU therapy in the EU in more than a decade, supported by Phase III LIBERTY-CUPID data showing significant itch and hive reduction at 24 weeks

University of Liverpool scientists unveil Novltex, a powerful new antibiotic against superbugs

The groundbreaking synthetic antibiotic is effective against multidrug-resistant bacteria such as MRSA and Enterococcus faecium, offering a promising new weapon in the global fight against antimicrobial resistance

Lilly’s oral GLP-1 orforglipron outperforms semaglutide in Phase III head-to-head trial

The results highlight orforglipron’s potential as a once-daily oral therapy to help more patients achieve near-normal glucose levels and meaningful weight reduction

Amphista Therapeutics discloses first details of its SMARCA2 degrader programme

Amphista has identified SMARCA2 Targeted Glues, which induce protein degradation via a novel mechanism and enable the development of smaller and more drug-like molecules than conventional PROTAC binders

Genoskin raises $8.7m in its first funding round to advance its ethical, human-based alternatives to animal testing

The financing will drive Genoskin’s next phase of growth, with a view to scaling up operations in both the US and France

Tiziana receives grant for intranasal anti-CD3 monoclonal antibody therapy for spinal cord injury

The US Department of Defense awarded the biotechnology company a research grant to study the use of intranasal anti-CD3 therapy in traumatic spinal cord injury (SCI)

Novo Nordisk’s oral semaglutide scores EU approval for cardiovascular benefits

Rybelsus is now the first and only oral GLP-1 RA to reduce cardiovascular death, heart attack and stroke

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Guardtech support staff member’s epic trek for cancer charity close to the business’ heart

The Haverhill cleanroom construction specialists donated £500 to Sarcoma UK to support their IT & Systems Manager Elliott Sheppard’s 25km trek in honour of his daughter...

Kindeva to showcase complex drug delivery expertise at CPHI 2025

Global CDMO highlights sterile injectable, pulmonary, nasal and dermal capabilities

SynGenSys introduces NK.SET synthetic promoter library to advance natural killer cell therapies

First commercially available NK (natural killer) cell-specific promoter library enables precise and controllable gene expression

Takara Bio launches Cellartis MSC EV Wonder: a defined, xeno-free medium for high-yield EV production

As the field shifts from MSC-based approaches to MSC-EVs, researchers are seeking solutions that deliver both robust yields and reproducible quality at scale

Robust and flexible cell lines that fit your strategy

Mammalian platforms that deliver a new standard of excellence

Testo Saveris showcases comprehensive pharma monitoring system at CPHI 2025

Automated system delivers precision, traceability, and compliance across the supply chain

Shimadzu enhances dual ion source technology with compact LCMS-2050

The system combines high-speed analysis, energy efficiency, and advanced DUIS capability in a compact design

Titan develops bespoke calibration rig for ultra-low flow measurement

Company designs state-of-the-art system to support next-generation ultrasonic flowmeters

Sapio Sciences introduces world’s first 3rd-generation ELN

Sapio ELaiN is an AI-powered lab notebook designed to act as a scientific collaborator

L.B. Bohle to showcase machines for OSD, food and nutraceuticals at PACK EXPO 2025

Company to present advanced blending, particle sizing and coating technologies at Las Vegas event

Anton Paar launches next-generation rheometers for unmatched precision

New instrument series redefines possibilities in rheological testing and analysis

Douglas Pharmaceuticals sets new benchmark for capsule quality with CI Precision

Partnership delivers compliance confidence, efficiency gains and reduced waste

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