Olympus Group
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Drug Delivery
Improving delivery with macrophage targeting
The maladaptive action of macrophages are increasingly problematic in conditions such as rheumatoid arthritis and inflammatory bowel diseases, while certain macrophage subtypes are also known to promote tumour growth and metastasis. The advanced stealth liposome approach to drug delivery selectively targets macrophages and presents a potentially effective treatment strategy. Central to the evaluation of this approach was the technique of confocal laser scanning fluorescence microscopy using the fully automated Olympus FluoView FV10i system.