Dose unattended exothermic reactions safely
Demand for safer, automated chemical R&D in the organic synthesis lab includes the need for unattended dosing while controlling the reaction temperature
Mettler Toledo has launched a new volumetric dosing algorithm for EasyMax and OptiMax synthesis workstations that allows unattended dosing combined with safe reaction temperature control.
The latest synthesis workstation touchscreen firmware allows the user to enter the maximum reaction temperature for a dosing operation, which is particularly advantageous for exothermic reactions. If the reaction exceeds the pre-programmed maximum temperature, dosing will pause and resume only after the reaction temperature cools down to below the maximum.
During an EasyMax or OptiMax experiment, scientists can run volumetric dosing with the plug-and-play operated Dosing Unit SP-50. Dosing can be started manually or pre-programmed as part of a task sequence. Dosing a specified amount of liquid can be controlled by dosing time or rate.
Strongly exothermic reactions can cause the reaction to rise above the desired temperature even with the powerful cooling capability of EasyMax and OptiMax. In some cases, such a rise in temperature could cause a decrease in reaction selectivity, formation of undesired products and even an uncontrollable reaction.
The new functionality allows unattended dosing without any risk – even if there is no understanding of the exothermicity of a dosing controlled reaction. The dosing algorithm safely controls the reaction temperature. Please visit the synthesis workstations page for additional information on product features and details.
