The pharmaceutical industry constantly seeks to improve drug delivery methods to enhance patient outcomes. One notable advancement is the development of Hydroxypropyl Methylcellulose (HPMC) capsules by Qualicaps. These capsules have become a reliable solution for delivering drugs, especially for hygroscopic and moisture-sensitive applications, addressing the needs of pharmaceutical and nutraceutical companies globally.
The evolution of HPMC capsules
HPMC capsules have gained popularity due to their chemical and physical stability compared to traditional gelatin capsules. Their plant-based origin also makes them suitable for vegetarians, vegans, and individuals with dietary restrictions related to animal products. Qualicaps has advanced this technology by designing and refining the manufacturing processes to improve the performance and usability of these capsules.
Advanced manufacturing for superior quality
HPMC capsules can be produced using either the cold gelling method or the thermal gelling method. Qualicaps pioneered and patented HPMC capsule, Quali-V®, using the cold gelling technique. This method enhances the mechanical properties of the capsules, making them more robust and less prone to breakage during handling and transportation, thereby ensuring the integrity of the encapsulated contents.
Additionally, the cold gelling method contributes to more consistent dissolution profiles, which is crucial for the effective delivery of active pharmaceutical ingredients (APIs). This consistency improves bioavailability and therapeutic efficacy, ensuring patients receive the intended dosage more reliably. Stability is another critical factor in the pharmaceutical industry. Qualicaps HPMC capsules demonstrate superior stability, particularly regarding moisture content and temperature fluctuations. This stability protects sensitive ingredients, extending the shelf life of products and maintaining their efficacy over time.
One of the significant innovations from Qualicaps is the introduction of an extra dried version of its HPMC capsules. Designed for highly hygroscopic and moisture-sensitive formulations, these extra dried capsules have very low moisture content, ensuring that even the most delicate formulations are effectively encapsulated and protected throughout their shelf life.
Compliance and sustainability
Qualicaps HPMC capsules meet stringent regulatory standards for pharmaceutical and nutraceutical applications. This compliance ensures that manufacturers can produce high-quality products that adhere to global health and safety standards.
The cold gelling method used in the production of Qualicaps HPMC capsules also aligns with sustainable manufacturing practices. This method requires less energy than the thermal process, reducing the overall carbon footprint, further minimising environmental impact and promoting sustainable pharmaceutical manufacturing.
Market relevance
With a growing consumer base prioritising health, sustainability, and dietary restrictions, Qualicaps HPMC capsules are well-positioned in the market. Their plant-based origin, coupled with superior quality and stability, makes them an appealing choice for a wide range of consumers.
Qualicaps HPMC capsules represent a significant advancement in drug delivery technology. Their superior quality, enhanced stability, and sustainable production processes make them an ideal choice for pharmaceutical and nutraceutical applications. The introduction of the extra dried version further addresses specific industry needs for hygroscopic and moisture-sensitive formulations. As the industry continues to evolve, Qualicaps remains a key player, providing innovative solutions that improve patient outcomes and support sustainable manufacturing practices.
Qualicaps' legacy and integration with Roquette
Qualicaps has built a strong reputation as a trusted partner for leading global pharmaceutical and nutraceutical companies. Their expertise in capsule technology and commitment to quality ensures they continue to meet the evolving needs of the market.
Qualicaps is a global player in the manufacturing and commercialisation of hard capsules and pharmaceutical processing equipment for the oral dosage market. With over 125 years of capsule manufacturing experience and the introduction of several capsule innovations to the pharmaceutical market, Qualicaps is uniquely positioned to provide an integral service to its customers through its global team of commercial, scientific, and technical experts. Since October 2023, Qualicaps has been part of Roquette, a global leader of plant-based ingredients for health and nutrition markets that operates in more than 100 countries, through more than 30 manufacturing sites, and employs around 10,000 people worldwide.
