Cell support matrix improves productivity

Ashby Scientific, of Coalville in the UK, has launched ImmobaSil, a cell support matrix that is claimed to offer advantages over traditional microcarriers. Said to support the growth of both adherent and suspension cells in culture, the support matrix has a porous structure that gives a very large surface area.

The gas-permeable silicon matrix enhances oxygen transfer, significantly extending the life-span of long-term cultures, while the design of the pores ensures optimal nutrient flow, allowing cell densities in excess of 1 x 108 to be achieved.

ImmobaSil's surface properties encourage cell adhesion in serum-free conditions, while its mechanical strength protects them from shear forces. It is inert, non-toxic, resistant to biological and chemical attack and can be repeatedly sterilised with steam or chemical reagents.

The matrix is supplied pre-wetted and comes in a range of formats suitable for use in a wide range of fermenters and culture vessels.