Dynamic approach to solubility challenges in liquid chromatography

Published: 8-May-2008

UK liquid chromatography innovator Dynamic Extractions has extended its range of HPCCC instruments by adding the Spectrum HPCCC.

UK liquid chromatography innovator Dynamic Extractions has extended its range of HPCCC instruments by adding the Spectrum HPCCC.

HPCCC instruments allow chemists to use liquid stationary phases and their inherent advantages of high capacity and improved solubility characteristics to solve their everyday challenges. Rather than the solubility of samples being a limiting factor, the sample can be injected onto the column in either the mobile, stationary or a mixture of both phases without affecting the performance of the chromatography.

The Spectrum HPCCC instrument is specifically designed with discovery and development chemists in mind. It allows the separation of samples that are difficult to solubilise, firstly at milligram scale to develop purification methods, and then to scale that method to semi-prep scale, allowing chemists to purify 1-2 gram crude material per injection. This bench-scale instrument allows upwards of 20 grams of crude material to be processed every eight hours.

You may also like