EMBL chooses CodeLink for study of molecular mechanisms in tumour growth
The European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, has selected the CodeLink Bioarray system from Amersham Biosciences to perform gene expression experiments in its developmental biology unit, and genomics core facility (GeneCore).
The European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, has selected the CodeLink Bioarray system from Amersham Biosciences to perform gene expression experiments in its developmental biology unit, and genomics core facility (GeneCore).
The mammalian organogenesis and endocrinology research group within the developmental biology unit is using the mouse as its model system to carry out studies to better understand the underlying molecular changes in the transformation of pituitary tumours from the benign to the aggressive malignant stage. The scientists working on this problem required a microarray platform that contained most of the annotated mouse genes available today, and also needed to reliably record changes in expression levels of low abundant genes. The CodeLink UniSet Mouse 20k Bioarray was used to carry out expression profiling on the different pituitary tumour stages to gain a complete picture of these expression profile changes.
The CodeLink Bioarray platform includes ready-to-use microarrays of mouse, rat, and human genes for gene expression profiling as well as a ready-to-use microarray of single nucleotide polymorphisms (SNPs). New CodeLink Custom Bioarrays are available as a service to provide either CodeLink Custom Rearrays, which is prepared using tailored subsets of existing CodeLink mouse, rat, or human genes, or SNPs, or as CodeLink de novo Bioarrays, which is prepared using gene content provided by the customer.