Freeman Technology highlights relevance of the FT4 for DPI characterisation

Published: 2-Mar-2010
Manufacturing Regulatory Drug Delivery Analysis Pharmaceutical

Respiratory Drug Delivery (RDD) 2010, 25 - 29 April 2010, Florida, US

At Respiratory Drug Delivery (RDD) 2010, Freeman Technology will highlight the unique insight the FT4 Powder Rheometer offers DPI formulators. This message will be reinforced by a presentation of work from the University of Bath showing a direct correlation between the measured dynamic powder properties and fine particle dose (FPD), a measure of drug delivery efficiency.

Dynamic powder characterization with the FT4 directly quantifies powder flowability and the response of a formulation to air, a critical property for successful DPI development. To ensure efficient drug delivery a DPI formulation/device combination must be engineered to achieve aerosolisation of the dose to a respirable size during use.

Research at the University of Bath has shown a robust correlation between FPD and aerated energy, a measure of how the flowability of the powder changes with the amount of air flowing through it. This makes the FT4 an extremely useful tool for the development of DPI formulations, which are required to disperse easily, with more consistent and less patient dependent performance.

The FT4 combines dynamic testing methodologies with shear and bulk property measurement, to provide comprehensive, process relevant powder characterisation. Precision engineering in combination with well-defined, automated test procedures deliver exceptional reproducibility and sensitivity. With application know-how that has been gained from 10 years working with industry, Freeman Technology also provides extensive powder processing expertise alongside the FT4 Powder Rheometer.
See more

You may also like

Manufacturing

Viatris to cut 10% of its global workforce after Indian plant fire

Read more
Viatris has lowered its profit outlook for 2026 after a fire in February shut down a key plant in Nashik, India. Despite this, the company reported stronger-than-expected revenue and announced a restructuring plan

Trending Articles

  1. Echo MS+ integration enhances high-throughput mass spectrometry SCIEX expands compatibility with the ZenoTOF 8600 system to deliver greater sensitivity and automation capabilities
  2. Drug-loaded pellets: unlocking flexible oral dosage design with modern pelletisation technologies Produced using advanced extrusion–spheronisation technologies such as GEA’s NICA systems, drug-loaded pellets are gaining traction as a flexible and scalable oral solid dosage platform that enhances release control, patient outcomes and manufacturing efficiency
  3. You need to be a subscriber to read this article.
    Click here to find out more.
    Automated visual inspection: reducing false rejects with intelligent bubble masking This article explores how intelligent bubble masking in automated visual inspection systems can significantly reduce false rejects in biopharmaceutical manufacturing by accurately distinguishing harmless bubbles from harmful particles
  4. CARBOGEN AMCIS and Celonic unveil integrated ADC development platform at World ADC London 2026 The strategic alliance combines biologics and highly potent payload capabilities to streamline ADC development and manufacturing

Upcoming event

DCAT Week

23–26 March 2026 | Conference | New York, US See all

You may also like

Manufacturing

Viatris to cut 10% of its global workforce after Indian plant fire

Viatris has lowered its profit outlook for 2026 after a fire in February shut down a key plant in Nashik, India. Despite this, the company reported stronger-than-expected revenue and announced a restructuring plan
Regulatory

CStone's sugemalimab approved by MHRA for Stage III NSCLC

The MHRA's decision marks the biopharma's second indication approved for the product in the UK, with a global commercial rollout for sugemalimab now actively underway
Manufacturing

GEA opens new technology centre in Germany

The opening of the new technology centre for pharmaceutical freeze-drying systems will strengthen the supplier's position in the growing pharmaceutical applications market
Regulatory

American Chemistry Council's statement to Trump: make chemistry in America again

The Council has released a statement ahead of the President's State of the Union Address, asking for policies that unlock domestic production and address unfair foreign practices
Regulatory

Johnson & Johnson files FDA application for IMAAVY in wAIHA

Johnson & Johnson has submitted an sBLA to the US Food and Drug Administration seeking approval of IMAAVY as the first-ever treatment for warm autoimmune haemolytic anaemia, supported by Phase II/III ENERGY trial data showing rapid and durable haemoglobin response
Manufacturing

Avoiding product degradation with a low-temperature, vacuum cake dryer

High-performance chemicals often lose efficacy when exposed to heat. Active pharmaceutical ingredients (APIs), fine chemical intermediates, and biologically derived materials are subject to product degradation and can transform, or lose potency under high drying temperatures. This thermal sensitivity demands precise control to maintain molecular stability and ensure product quality
Manufacturing

Cutting-edge customer projects - Specialised systems for multiple sectors

As specialists in laboratory and process chemistry equipment solutions, Labtex have expertise in designing, manufacturing, and installing customised systems for a diverse range industries and disciplines – including chemical manufacturing, drug development, and metals recovery
Subscribe now