GSK enters into agreement with US Biosynexus
GlaxoSmithKline Biologicals (GSK Biologicals), the vaccine research, development and production centre of GSK , has entered into an exclusive collaborative agreement with Biosynexus to develop and commercialise staphylococcal antibodies and vaccines to prevent and treat infections caused by staphylococci bacteria.
GlaxoSmithKline Biologicals (GSK Biologicals), the vaccine research, development and production centre of GSK , has entered into an exclusive collaborative agreement with Biosynexus to develop and commercialise staphylococcal antibodies and vaccines to prevent and treat infections caused by staphylococci bacteria.
Biosynexus' lead product in its extensive development pipeline, BSYX-A110 monoclonal antibody for preventing staphylococcal infections in neonates and adults, is included in the agreement. The compound is currently in clinical trials in premature babies at multiple sites across the US. Phase I adult trials met safety and tolerability targets, and also demonstrated very good pharmacokinetic and pharmaco-dynamic capabilities, the company says.
The parties will co-develop BSYX-A110 monoclonal antibodies currently in clinical development to enable GSK Biologicals to develop a staphylococcal vaccine using Biosynexus antigen discovery and conjugation technologies. Biosynexus will co-promote monoclonal antibody technology in the US and share in the profits. GSK Biologicals will market the product outside the US and Biosynexus will receive royalties.
'This collaborative agreement will combine Biosynexus' expertise in monoclonal antibodies and vaccines for the treatment of hospital-acquired infections with GSK Biologicals' strong track record in developing biologicals and bringing vaccines to market worldwide,' said Jean Stephenne, president and manager of GSK Biologicals.