Halocarbon increases fluoro-based intermediates offering
Supplier of specialty fluoro chemicals, New Jersey-based Halocarbon has further increased its portfolio of trifluoroacetone derivatives, used as building blocks for producing fluorinated derivatives with pharmaceutical and other applications.
Supplier of specialty fluoro chemicals, New Jersey-based Halocarbon has further increased its portfolio of trifluoroacetone derivatives, used as building blocks for producing fluorinated derivatives with pharmaceutical and other applications.
In addition to 1,1,1-trifluoroacetone, the company has developed the derivatives: 3-bromo-1,1,1-trifluoroacetone, 3,3 dibromo-1,1,1-trifluoroacetone, 3-chloro-1,1,1-trifluoroacetone and 1,1,1-trifluoroisopropanol.
The company says that these compounds can offer faster, more efficient reaction routes that save energy costs and speed time to market. For example, the protons on 1,1,1-trifluoroacetone are more acidic compared with acetone, thus mild basic conditions are required to make the enolate of trifluoroacetone. This makes the molecule ideal fro preparing compounds containing a CF3 group. The bromo analogue was recently used to produce molecules for treatment of artherosclerosis and other coronary artery diseases.
The company says that it is seeing increased demand for the fluoro compounds in both the pharma and agro sectors. "In challenging economic times like those we are in now, the most efficient process gives us and our customers a key strategic advantage," said Halocarbon ceo Peter Murin.