Integrating chemical and clinical information

ChemNavigator and BioSpace have created a way of integrating their internet-accessible chemical information and clinical development tracking systems. Researchers will be able to apply information about compounds being developed by their competitors to decisions about compound selection in the early stages of their own research. It gets around the problem of integrating disparate data sources and types by applying data mining tools to the databases.

ChemNavigator's iResearch System is an informatics system that provides chemical structure-based data mining tools, and includes more than three million chemical structure records linked to current data from FDA approved drugs, through patents, to research compounds that are available from many different sources around the world. BioSpace's Clinical Competitive Intelligence System is a text-based knowledge management system that provides information on 350 disease targets through the tracking of compounds in various stages of development.

By linking the two systems, users can be notified when compounds they are considering are similar to compounds that are already in clinical development. Users will be able to identify structurally similar screening compounds and related scientific information, such as patent status, toxicology profile and biological screening data without having to dig through many different data sources, comparing structure-based chemical information with text-based biological data.