Matsushita measures cholesterol in one drop

Published: 30-Apr-2001


A compact sensor which can measure total blood cholesterol from a single drop of blood has been developed by Matsushita Electric Industrial Co. The measurement can be completed in about three minutes using a blood sample of 2;3µl. Most blood testers work on the blood sample after it has been processed in a centrifuge to separate the plasma from the red and white blood cells.

The new sensor incorporates a high efficiency filter that extracts plasma. The filter is constructed from glass fibers that block the passage of red and white blood cells without rupturing them. The sensor is shaped like a flat plate nearly 4x1 cm. The filter blocks out blood cells that would otherwise interfere with the measurement, allowing passage of the plasma containing the cholesterol.

Testing takes place through an oxidation-reduction reaction between the cholesterol and an enzyme reagent. This chemical reaction generates an electric current, whose measurement is used to calculate the total amount of blood cholesterol.

Matsushita plans to develop a blood cholesterol monitor based on the new sensor that can be used by individuals at home. It will also continue research to develop technology for the simultaneous measurement of blood glucose levels.

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