Microwaves promote chemical reactions

UK-based CEM, of Buckingham, has designed a microwave accelerated reaction system to enhance the synthetic chemist's ability to promote chemical reactions under controlled conditions on a laboratory scale. The Discover Synthesiser facilitates either homogeneous or heterogeneous solution phase chemistry, solid phase reactions and chemistry conducted on solid supports.

It uses vessels from 5ml to 100ml for reactions run under atmospheric conditions, and a 10ml vessel with septa for reactions run at elevated temperatures and pressures. Its primary uses are in the discovery and lead optimisation phases of new product development processes with potential benefits of reduced reaction times, pathway simplification, and improved yields and purity.

The microwave absorption properties of some liquid and solid materials, due to their polar and ionic characteristics, have the capability to significantly enhance chemical reactions relative to traditional heating methods, and the technique provides chemists with unique opportunities, the company says.