MorphoSys sign deal to further cancer treatment

Published: 25-Mar-2008
Sustainability

German company MorphoSys has signed an agreement with Dutch biotech specialist Crucell and technology partner DSM Biologics to allow the PER.C6(R) cell line to be used in the production of clinical grade material for the development of its proprietary therapeutic cancer antibody programme MOR202.


German company MorphoSys has signed an agreement with Dutch biotech specialist Crucell and technology partner DSM Biologics to allow the PER.C6(R) cell line to be used in the production of clinical grade material for the development of its proprietary therapeutic cancer antibody programme MOR202.

MOR202 is a fully human HuCAL antibody directed against CD38, a therapeutic target for the treatment of multiple myeloma and certain leukaemias.

This set-up brings together a fully human antibody to treat blood-borne cancers with production capabilities in the same fully-human environment. Manufacturing human antibodies in such a manner offers several potential advantages over alternative production methods.

"Today's news shows that MorphoSys's MOR202 programme is on track towards the next development stages - formal pre-clinical development in 2008 and 2009 and the filing of an application for clinical trials early 2010," said Dr Marlies Sproll, chief scientific officer of MorphoSys. "Based on the positive experiences we have gained with Crucell's cell line and DSM's manufacturing capabilities within our lead program MOR103 we have chosen to continue to use this set-up for MOR202."

Financial details on these agreements were not disclosed.

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