Aptar Pharma presents DF30Plus for pDMIs

Incorporating a Cyclic Olefin Copolymer (COC) neck gasket to further enhance its performance

DF30Plus with COCe

Aptar Pharma, a global provider of aerosol, injection and spray delivery systems for biotech, healthcare and pharma products, will present its latest innovation, DF30Plus with COCe, this week (9–11 December) at the Drug Delivery to the Lungs (DDL) conference in Edinburgh, Scotland.

The DF30Plus metering valve spray delivery system incorporates a Cyclic-Olefin-Copolymer (COC) neck gasket to further enhance its performance. COC is a well-known and characterised material used for injectable drug containers. COCe is a specific version of COC that has unique elastomeric properties while being ultraclean and inert.

The new version of the DF30Plus incorporating a neck gasket manufactured with COCe offers several key benefits:

  • Step change improvement as a barrier to leakage
  • Ultra low extractible level
  • Compatibility across a wider range of drug formulations, including ethanol-containing formulations

  • Suitable for all pMDI filling technologies
  • Robust design for accurate and consistent performance

'Thanks to the introduction of our novel COCe within our DF30 valve technology platform, Aptar Pharma is able to offer a series of key advantages to meet the evolving needs of our customers; including improved compatibility with both EtOH containing and dry drug formulations, superior cleanliness and improved leakage barrier characteristics which result in a more robust and less crimp sensitive manufacturing process,' said Chris Baron, Associate Director, Business Development, Aptar Pharma.

Aptar Pharma specialises in aerosol metering valves for pMDIs for the treatment of asthma and COPD and each year produces several hundred million metering valves in three manufacturing facilities located across Europe and Asia. Aptar Pharma designs, develops and manufactures its own elastomer gaskets – a key component of the valve – within its unique in-house Elastomer Centre.

Aptar Pharma has been constantly evolving the DF30 metering valve technology platform for more than 20 years.

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