Resources available for named reactions in organic synthesis

Published: 7-Dec-2022

Thermo Fisher Scientific provides an eBook and video resources covering many reactions used in manufacturing chemistry

Some of the most common and useful chemical reactions used in organic synthesis are named after the chemists that discovered them. To celebrate these reactions and the chemists whose names they’re known by, Thermo Fisher Scientific has published an eBook and video series on this topic.

The eBook, now available for download, offers ten chapters of rich content covering more than 45 noteworthy reactions. This resource organizes the reactions into the following categories:

  • Transition metal-catalyzed couplings
  • Reactions involving carbonyl compounds
  • Electrophilic aromatic substitution reactions
  • Nucleophilic substitution reactions
  • Rearrangement reactions
  • Oxidation reactions
  • Reduction reactions
  • Electrophilic addition reactions
  • Free radical reactions
  • Heterocycle formation reactions

Content includes a brief history of each reaction’s discovery, its mechanism, advantages, and real-world applications of each. These real-world applications include how these reactions are used in the large-scale manufacturing of anti-cancer and antimalarial drugs, and other interesting molecules. 

Within each chapter of the eBook, at least one reaction is given additional attention and focus. This increased depth of coverage for these focus reactions includes relevant reaction protocol details and a product selection guide to enable easy procurement of the reagents (e.g., acids, bases, solvents, catalysts, etc.) needed to perform these reactions in your lab. 

Focus reactions with these additional resources include:

  • Suzuki cross-coupling reaction
  • Grignard reaction
  • Friedel-Crafts acylation and alkylation reaction
  • Baeyer-Villiger oxidation 
  • Beckmann rearrangement reaction
  • Dess-Martin reaction
  • Clemmensen reduction
  • Simmons-Smith cyclopropanation reaction
  • Wohl-Ziegler bromination

Each of these focus reactions is also the topic of an animated video that provides a fun, quick, and accessible way to learn about each reaction and what advantages is has to offer in your manufacturing work. 

You can access both the eBook and video series on the organic chemistry resources page of

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