Thermo Fisher Scientific and ChromSword, a software provider, have collaborated to launch an automated high performance liquid chromatography (HPLC) and ultra-high performance liquid chromatography (UHPLC) method development system, designed to enable chromatographers to deliver robust and validated methods in less time and with higher confidence.
The Vanquish method development HPLC and UHPLC system provides an integrated, network-deployable solution for automated method development and validation for diode-array, charged aerosol and mass spectrometric detection, the company says. The system combines the Vanquish HPLC and UHPLC systems and the company’s Chromeleon chromatography data system (CDS) with ChromSwordAuto and AutoRobust software.
It uses AI to minimise manual interaction and enables method creation for complete compound detection with no prior sample knowledge required. The system incorporates multiple detection capabilities, while the integrated Chromeleon Data Vault is designed to reinforce data integrity and compliance.
"Liquid chromatography method development is an incredibly time-consuming and labor-intensive process. To efficiently develop robust methods, frequent manual interactions and extensive method development experience are critical," said Christoph Nickel, Senior Director Software Marketing, Thermo Fisher. "The Vanquish Method Development HPLC and UHPLC system solves this challenge by allowing our customers to automate method development and validation, saving time and eliminating prerequisite expert user knowledge."
Dr Sergey Galushko, Head of R&D at ChromSword, said "Chromeleon CDS and ChromSwordAuto are two of the most powerful chromatography software systems available. By combining the intelligent method development capabilities of ChromSwordAuto with Chromeleon software’s flexible instrument control functionalities, we’re providing users with a complete suite of method development and validation tools. Through this package, a substantial reduction in method development time is possible for Chromeleon CDS users working with small and large molecules."
The system also offers method flexibility for pharmaceutical, biopharmaceutical, chemical and food testing laboratories, with automated column switching and universal analyte detection, and mass spectrometry-based peak tracking capabilities for more reliable results. Through its automation features, the system is positioned to meet changing needs of laboratories as they look to implement broader digitalization strategies and reduce on-site personnel.
