Thermo Fisher wins innovation gold


Thermo Fisher, BASF and Zeon Corporation win the top prizes at the CPhI Innovation Awards

Following presentations to the judging panel yesterday, the winners of the best pharmaceutical innovations at the show were announced at the exhibitor party on Tuesday evening.

Thermo Fisher Scientific took the Gold for its advanced technology of Raman spectrometry packaged in a very small, robust and easy-to-use instrument that can test incoming raw materials with the press of a button. The results require no sophisticated interpretation rather give a simple ‘pass’ or ‘fail’ result for a given material.

The Thermo Scientific TruScan allows customers to realise huge time and cost savings and to improve quality processes. In many cases, it allows users to test a greater proportion incoming materials on the loading dock or on the warehouse floor, rather than only testing a statistical sample.

In addition, TruScan can scan materials right through transparent packaging. In doing so, it allows many materials to be identified without opening them, such as frequently counterfeited drugs like Heparin, malaria tablets and Viagra. As a result, TruScan saves customers a significant amount of time and money.

BASF won silver for its innovation Soluplus, a new chemical entity and the first excipient in the market especially designed to form stable solid solutions via hot melt extrusion.

Hot melt extrusion has become increasingly important in pharmaceuticals due to its ability to molecularly dissolve a novel drug in a solid solution. Soluplus opens new doors to pharmaceutical innovation by enabling many promising drug candidates to reach the market that could not have been formulated with conventional excipients.

The Bronze prize award went to Zeon Corporation for its high performance ether solvent, CycloPentyl Methyl Ether (CPME), for process innovation and green chemistry.

This new solvent is an alternative to ether solvents such as THF, diethylether and dioxane, which have some inherent drawbacks of low boiling point, easy peroxide formation, easy solubility in water and inefficient recovery from water.

CPME’s features include high boiling point (106°C), as well as preferable characters: low formation of peroxides; relative stability under acidic or basic conditions; formation of azeotropes with water; a low affinity for water; and small evaporation energy compared with other ethers coupled with narrow explosion range.

These advantages enable some conventional reaction sequences in one pot or easier process as a result of solvent unification and facile isolation of the products, which contribute green chemistry and cost reduction.

The CPhI show, which opened in Paris on 5 October, expects to surpass the 25,000 visitor numbers that passed through the doors last year in Madrid.