Pfizer to use Prosonix" sonocrystallisation technology for primary API manufacturing

Published: 16-Sep-2008
Manufacturing Ingredients Research & Development

Pfizer Global Manufacturing is to implement UK-based Prosonix" Prosonitron reactor and sonocrystallisation process technology at its manufacturing facilities in Ireland.


Pfizer Global Manufacturing is to implement UK-based Prosonix" Prosonitron reactor and sonocrystallisation process technology at its manufacturing facilities in Ireland.

The Prosonitron technology will be used in the controlled crystallisation and production of a number of Pfizer products, and follows an extended period of collaboration and testing with Pfizer Global Research and Development in Sandwich (UK).

Proven across scale, the technology is facilitating the Complete Crystallization Control of many aspects of complex pharmaceutical crystallisation processes, including control of crystal size, shape and purity, the selective production of polymorphs, enhancing both manufacturing productivity and the ultimate formulation performance of the drug product. The technology is increasingly being recognised as an important new option in pharmaceutical API crystallisation.

This latest pharmaceutical related deal with Pfizer underscores Prosonix" leadership in taking advanced ultrasonic particle engineering technologies to commercial scale, said ceo David Hipkiss.

"Sonocrystallisation technology offers an additional tool to augment existing techniques for API crystallisation and in-situ selection of specific API physical characteristics," added Simon Davidson, new product team leader, Pfizer Global Manufacturing. "We look forward to working with the Prosonix team to implement this technology in Pfizer Global Manufacturing."

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