Providing less invasive drug delivery with biopolymers

Published: 3-Dec-2014

Evonik is currently working on a German Federal Ministry-funded project to find oral delivery solutions for injectable biopharmaceuticals. One route to producing less invasive therapeutic options involves using next-generation biopolymers

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It is a given that medications should work. But they can do so only if the active reaches its targeted location in the body and remains in place long enough and at a high enough concentration. Evonik says biodegradable polylactides (polylactic acids) and their copolymers, which the company markets under the brand names Resomer and Resomer Select, are especially suited to create sustained release formulations for modern drugs that are injected.

Although most medications are taken orally, e.g. as tablets or capsules, many modern protein or nucleic acid-based biotherapeutics, such as those used to combat cancer, diabetes or multiple sclerosis, must be administered by injection – under the skin (subcutaneously), into the muscles (intramuscular), or directly into the vein (intravenously).

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