As RNA research grows in scale and complexity, researchers need tools that can keep pace with more challenging samples and advanced analysis. Invitrogen SuperScript V Reverse Transcriptase is a next-generation engineered enzyme designed to make the critical step of converting RNA to cDNA faster, easier and more flexible.
SuperScript V combines strong performance with room-temperature stability and simpler setup. Available as a standalone enzyme and in ready-to-use master mix formats, it supports workflows ranging from individual experiments to high-throughput and automated cDNA synthesis.
Our goal is to empower researchers to move from sample to insights faster and with greater confidence. With SuperScript V, we’ve taken what researchers have trusted about SuperScript for decades and redefined what’s possible with faster, more flexible and highly stable RNA-to-cDNA synthesis.
Said Pawan Singh, vice president and general manager, molecular biology, Thermo Fisher Scientific.
Key customers and applications:
- Molecular biology and genomics researchers: Scientists performing RNA-to-cDNA workflows for gene expression, sequencing and transcriptomics.
- Researchers working with challenging RNA: Scientists analysing low-input, degraded, inhibitor-rich or other difficult RNA samples.
- High-throughput laboratories: Core labs and other research teams processing larger numbers of samples manually or through automated systems.
Features/benefits:
- More flexible setup: Reactions can be prepared at room temperature, with assembled reactions remaining stable for up to 24 hours, giving researchers more flexibility to batch samples, manage delays and support manual, high-throughput and automated workflows.
- Faster workflows: Speedy cDNA synthesis enables target detection with reaction times as short as one to 10 minutes, helping shorten an important step in RNA analysis.
- Excellent performance: Supports sensitive, high-quality cDNA synthesis across a broad range of RNA samples, with thermostability up to 65°C.
- Simplified workflows: DTT-free formulations and ready-to-use master mix options help reduce preparation and pipetting steps, while reduced cold-chain requirements provide greater flexibility in reagent handling and shipping.