Universal HPLC detector offers near nanogram sensitivity

Published: 6-May-2010
Manufacturing Research & Development Analysis

NQAD is said to be a major advance in high-performance liquid chromatography detection

Dorton Analytical, a UK supplier of laboratory equipment, says its ultra-sensitive, universal Nano Quantity Analyte Detector (NQAD) is a major advance in high-performance liquid chromatography detection.

The NQAD is a different kind of aerosol-based detector for HPLC, the company says. Based on Condensation Nucleation (CNLSD) technology, the NQAD has the ability to detect sub-nanogram levels.

Benefiting from ultra-high sensitivity, the detector is suitable for searching for drug impurities, degradation products, excipients and when industrial hygiene is a concern. Both easy and hard-to-measure compounds can be quantified accurately with minimal sample preparation, the company says.

The NQAD detector also offers a wide dynamic range with superior linearity compared with other aerosol-based detectors. Chromophores and fluorophores are not needed for detection, thereby eliminating or decreasing the need for compound derivatisation. The detector is optimised for use in UHPLC, HPLC and SFC.

The company says it is easy to install and operate and therefore ideal for use in any laboratory.

See more

You may also like

Manufacturing

Setting standards for polymer and protein characterisation

Read more
SEC-3010 triple detector system uses GPC/SEC

Trending Articles

  1. 3PBIOVIAN and Colombia's National Cancer Institute partner to develop first locally produced oncology biosimilar The CDMO has signed an agreement with Colombia's Instituto Nacional de Cancerología to develop a biosimilar monoclonal antibody for an oncology indication, with technology transfer planned to enable domestic manufacturing
  2. You need to be a subscriber to read this article.
    Click here to find out more.
    Moving with speed and scale: innovative, material-sparing approaches to accelerate clinical development As early-stage drug development is often hindered by limited API supply, rising costs and tight timelines, material-sparing technologies are helping companies to progress faster with less
  3. Why weight sorting should move earlier in OSD development Phillip Ruda explains how earlier weight intelligence can improve process understanding, reduce risk and accelerate learning cycles

Upcoming event

DCAT Week

23–26 March 2026 | Conference | New York, US See all

You may also like

Manufacturing

Setting standards for polymer and protein characterisation

SEC-3010 triple detector system uses GPC/SEC
Design & Build

ESTEVE CDMO expands spray drying and high-potency containment capacity at Girona facility

ESTEVE CDMO has announced plans to add a 3000-square-metre production unit at its Celrà site in Spain to house additional spray drying equipment and high-potency containment suites, with the first new GEA spray dryer due online in Q1 2027
Research & Development

ProImmune and Roslin Institute collaborate to develop species-specific Ankyron binders for veterinary immunology

Immunological reagents specialist ProImmune has partnered with the University of Edinburgh's Roslin Institute to generate and validate novel species-specific binding proteins for porcine, bovine, avian and salmonid research, addressing a critical shortage of high-quality veterinary immunology reagents
Research & Development

Siemens Healthineers launches blood-based pTau217 and BDTau research assays for Alzheimer's and neurological disease

Siemens Healthineers has made two automated brain biomarker assays available for research use, offering scientists a less invasive blood-based alternative to cerebrospinal fluid testing for investigating neurological disease progression and early Alzheimer's detection
You need to be a subscriber to read this article.
Click here to find out more.
Analysis

Semaglutide patent cliff: pharma industry braces for impact

With the weight-loss industry shifting from a monopoly held by innovators to a high-volume, competitive generic market, the pharma manufacturing sector is gearing up for a "generic wave" with investments into large-scale protein synthesis and facilities for injectables
Manufacturing

Abzena named a leader in Frost & Sullivan ADC CDMO radar report

Recognition highlights integrated capabilities, proprietary technology and expertise in antibody-drug conjugates
Manufacturing

LabVantage Solutions introduces LabVantage CORTEX, advancing its LIMS platform for AI-driven laboratory operations

Next-Generation Platform Extends LIMS with Agentic AI and Cloud-Native Automation to Improve Efficiency, Reduce Errors and Gain Deeper Insight from Data. Learn More from LabVantage Leadership at Pittcon 2026
Subscribe now