Bristol-Myers Squibb automates new biopharmaceutical facility with Emerson
Global biopharmaceutical company Bristol-Myers Squibb (BMS) has selected Emerson Process Management to automate its new facility in Devens, Massachusetts, US.
Global biopharmaceutical company Bristol-Myers Squibb (BMS) has selected Emerson Process Management to automate its new facility in Devens, Massachusetts, US.
Emerson will apply its PlantWeb digital plant architecture, including the new Syncade smart operations management suite, DeltaV digital automation system and a network of intelligent digital field devices.
BMS is investing Euro 580m (US$750m) in the construction of the new Large-Scale Cell Culture (LSCC) manufacturing facility, which will have 120,000 litres of bioreactor capacity and produce biopharmaceuticals. The facility plans to be commercially operational in 2011.
The operational plan at the site is based on electronic workflow to reduce deviations, expedite batch review and release, improve real-time inventory management, and utilise industry and corporate standards.
The use of standards will enable quick response to product demand changes, as well as faster and more efficient technology transfer from research to product launch, the company says.
Integration of the real-time plant floor information with business enterprise processes is a key component. Operations management will use modular Syncade software for workflow processes including monitoring and controlling fully automated equipment, electronic work instructions, equipment status tracking, recipe driven operations, material tracking, automated weigh and dispense operations, electronic data capture, exception reporting, and the integration of operations workflow with enterprise resource planning.
The Syncade suite uses modular, scalable software to deliver operations management functionality in four critical areas: resource management, operations optimisation, integrated information, and quality & compliance. This software adheres to the ISA95 and ISA88 standards which reduce the time and cost required for design, documentation, implementation, testing, and verification of a project.
BMS is taking advantage of an integrated recipe design and execution environment that spans both manual and automated processes. This approach will automatically generate a comprehensive electronic batch record to meet regulatory compliance requirements, including electronic signatures.