Microfluidic Diffusional Sizing (MDS) is a novel technology which can be used to measure binding affinity and characterise protein interactions. MDS is complementary to current approaches such as surface plasmon resonance (SPR) and bio-layer interferometry (BLI) as interactions are monitored in solution, rather than on a sensor surface. Performing measurements in solution enables the analysis of samples that cannot be readily analysed using surface-based approaches.
In this article, Dr Sean Devenish, the Chief Scientist at Fluidic Sciences, discusses how the MDS technology can enhance the assay development process.
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