Formulation meets function: addressing palatability in drug development (part I)

Patient adherence to treatment regimens is inextricably linked to the palatability of medications, with consequences that can be far more serious than simply leaving a bad taste in one’s mouth

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However, drug developers face numerous challenges when creating truly patient-friendly dosage forms and must work within the strict constraints imposed by formulation requirements to avoid compromising therapeutic efficacy. 

Sophie Wallet Crouzet, Global Flavourist, and Lyzandra Passarella-Dutour, Global Taste Technical Director, Health, Nutrition and Care, at dsm­-firmenich, report.

This article explores some of these common challenges and examines how working with a panel of experts — from flavourists, scientists and regulatory specialists to consumer insight professionals — can help to overcome these barriers, leading to the development of medications that enhance patient compliance. 

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