The closures are designed specifically to seal threaded glass and plastic bottles and containers used for critical fluid transfer, media and buffer pooling and storage
DuPont has introduced the Liveo pharma bottle closures, which one-piece silicone stoppers and tubings made from biomedical-grade silicone elastomers, as a welcome addition to its existing overmolded assembly portfolio for biopharma processing applications.
The closures are designed specifically to seal threaded glass and plastic bottles and containers used for critical fluid transfer, media and buffer pooling and storage, and sample collection in biopharmaceutical and biotechnology processes.
“Adding a complementary range to the Liveo pharma overmolded assemblies (OMA) line demonstrates our commitment to meeting customer requirements in terms of supply flexibility and broader portfolio solutions,” said Michele Vigliotti, Regional Marketing Manager EMEA, DuPont Healthcare. “And the new pharma bottle closures deliver the same promises of product purity, performance, quality and reliability as the rest of our pharma product line.”
The product includes a one-piece silicone seal part made from biomedical-grade platinum-cured silicone elastomer molded with platinum-cured silicone tubing. This makes the product particularly suitable for preventing leak and contamination risk, the company says.
Both the silicone extruded tubing and molded parts are constructed with biomedical-grade silicone elastomers, designed to enable high purity by design.
The one-piece silicone seal part is designed to the end user’s specific needs and is manufactured and packaged in a clean manufacturing environment at the company’s FDA-registered healthcare industries materials site (HIMS) in Michigan, USA, which is dedicated to the manufacture of silicone-based materials for pharma and medical devices.
The products meet regulatory requirements and can be sterilised by autoclave and gamma irradiation for use in aseptic environments.
The cured silicone seal parts currently are available for GL45 and 38-430 neck bottles and containers. Silicone tubing is available in Shore A durometers of 50, 65 and 80. A range of tubing lengths and diameters can be accommodated according to the end-user’s specific needs. The number and dimensions of tubing pieces molded to the seal part are determined by the closure size.