Using oligonucleotides in the fight against COVID-19

Synthetic oligonucleotides, small pieces of single-stranded DNA and RNA made by chemical synthesis, have important uses in all aspects of molecular biology, genetics, medicine and beyond

ATDBio is an oligonucleotide synthesis company based in Southampton and Oxford, UK, specialising in making high quality oligonucleotides for demanding applications.

Synthetic oligonucleotides, small pieces of single-stranded DNA and RNA made by chemical synthesis, have important uses in all aspects of molecular biology, genetics, medicine and beyond. They have recently been a source of interest as the major component in COVID-19 testing kits. To meet the demand for oligonucleotides since the start of pandemic, ATDBio has scaled-up its production and purchased several more Shimadzu LC systems.

Dr Tom Brown Jnr, Director, said: “We synthesise oligonucleotides on different scales, from very small amounts for research purposes, to very large quantities of qPCR and LAMP primers and probes for COVID-19 tests. Having the ability to work reliably across a wide range of synthesis scales is crucial for us”.

Ian Tear, Senior Production Scientist, added: “We have the flexibility and knowledge to adapt our production processes to our customers’ needs. We take pride in finding simple, effective solutions to complex problems, allowing our customers to focus on their research”.

This knowledge and deep understanding of nucleic acid chemistry, combined with years of experience, are among the many reasons ATDBio is sought after for custom oligonucleotide synthesis. ATDBio continues to make a significant contribution to tackling the COVID-19 pandemic, as well as improving our preparedness for future outbreaks.

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Shimadzu UK (more information, website)