Powder Systems Limited (PSL), an international manufacturer of high containment isolators and gloveboxes for the pharmaceutical and biopharmaceutical industries, recently delivered a high containment installation and will start manufacturing a range of isolators for two projects in Spain.
In the first project, a large-scale pressure agitated nutsche filter dryer (ANFD) and a discharging isolator achieved a Design Occupational Exposure Limit (DOEL) of less than one mg during the sampling period.
This multipurpose isolator allows full recovery of the dried product obtained from the 0.6m2 filtration vessel plate, sampling without process disruption, powder dispensing, weighing and packing off within a safe and contained environment for the protection of both the operator and the product.
A leading Spanish pharmaceutical group will install these contained filtration and drying facilities during 2013 at its synthesis plant for the production of innovative medicines.
PSL is also working on a second Spanish project for a world leader in developing and manufacturing advanced pharmaceutical intermediates and APIs/HAPIs.
This high containment project includes two dispensing isolators, two SlurryBoxes (charging isolators for high potent slurry into reactors through pressured vessels), a reactor charging isolator and a vacuum drying isolator including PSL CakeStand Tray Dryer.
The whole high containment suite is designed for an OEB5 environment, achieving a DOEL of less than 100ng/m3 during eight hours Time Weighted Average (TWA). The six rigid isolators in stainless steel will be pre-tested and Factory Acceptance Tests carried out over the next few months and then installed in the user’s manufacturing site in Spain by the end of the year.
The partnership between the two companies has only just begun and future projects are being discussed to complement this first installation later in 2013.
PSL has been exporting to Spain for more than 10 years and expects further growth from the pharmaceutical and chemical markets.
To support this demand, PSL recently appointed a new agent, José Roldán Pázos, in July to represent the firm's standard product range.
This will enable PSL to have a direct presence in Spain and Portugal by adding the PSL simplefilter, a pressure filter plate with contained discharge, to his portfolio.
