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Market Reports
Is the production of biologic drugs ready for an overhaul?
Is the industry ready for a new manufacturing model? Mark Emalfarb, President and CEO of Dyadic International, thinks so and explains why to Dr Kevin Robinson
Leaders of transformation
Haig Armaghanian, founder and CEO of Haig Barrett, explores how synthetic biology pioneers are revolutionising therapeutic development
Continuous manufacturing: the facts and the future
Many companies talk about continuous manufacturing (CM), but few speak with the experience of actually implementing a continuous process line. Dr Kevin Robinson spoke to GEA’s Richard Steiner to find out why
Looking back on 2018 and making predictions for 2019
As the global pharmaceutical industry transitions from the knowns of 2018 into the unknowns of 2019, Dr Kevin Robinson caught up with some of the key players in the market to assess the year that was and the 12 months to come in terms of upcoming trends and developments
Serialisation is not enough
A global technology leader in supply chain security, Systech’s revolutionary solution provides authentic, safe and connected products throughout the pharmaceutical supply chain. Dr Kevin Robinson recently caught up with CEO Ara Ohanian to find out more
Preparing PIs for post EU-FMD success
Ian Haynes of Excellis Europe explains how the company’s unique approach to enabling collaboration between parallel importers is helping to simplify the transition to serialisation post EU-FMD
Eliminating the time thieves
Comprehensive scientific process engineering (CSPE) cuts delivery times and accelerates the commissioning of pharmaceutical systems. Dr Kevin Robinson spoke to Optima Pharma’s Gerhard Breu to find out more
Formulating for success with ODTs
An ageing global population, consumer demand for greater convenience and the need to improve patient compliance are driving the development of new platforms for orally disintegrating dosage forms
Choosing effective granulation strategies for effervescent formulations
Effervescent tablets and instant drinks are attractive dosage forms for healthcare companies looking to meet the needs of modern patients and consumers
FMD: clarification for wholesalers, distributors and logistics partners
Christian Taylor, Serialisation Business Consultant at Zetes, clears up some of the key pain points when it comes to the practical application of the Falsified Medicines Directive (FMD)
Serialisation and data connectivity: Part II
The new wrinkle in your supply chain, <a href='https://www.manufacturingchemist.com/news/article_page/Serialisation_and_data_connectivity_Part_I/147850'>click here to read part I</a>
Serialisation and data connectivity: Part I
The new wrinkle in your supply chain
A grandmaster’s approach to successful tableting
Tableting is a fundamental unit operation in the production of pharmaceutical oral solid dosage forms. Despite its long history of use and the development of innovations such as extended dwell times, unique technologies that independently and simultaneously measure and control both tablet weight and hardness, and a weight control system that provides increased sensitivity at lower forces, production problems still occur. Here, Dr Harald Stahl, Group Director, Application and Strategy Management, GEA, provides some troubleshooting tips from an unlikely source: the chess board
Discover, learn and connect at Lab Innovations!
Experience the latest developments at the UK’s only event dedicated to the laboratory industry
Pharmacovigilance in the hands of patients
Angharad Baldwin caught up with Dr Andrew Rut, founder of MyMeds&Me, at FutureLink 2018 to talk about what software as a service means to the pharmaceutical industry and the patient ... and whether there’s such a thing as too much data
ATP detection: The balance between precision and speed
Adenosine triphosphate (ATP) is an indicator molecule for the presence of biological residues used in food production. Burcu Yordem, 3M Food Safety, explains its role in an effective hygiene monitoring programme
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How onco-HPAPI manufacturing is adapting to a new era
The oncology landscape is undergoing a quiet but powerful shift. Pharmaceutical companies, once focused primarily on novel compounds, are now increasingly exploring repurposing opportunities with existing high-potency oncology APIs (onco-HPAPIs)
The economic advantages of continuous flow chemistry
Batch production has been the traditional workhorse of the pharmaceutical manufacturing sector. However, economic advantages are taking continuous flow out of the realm of a niche technology for high energy, hazardous reactions to become an essential part of the small molecule manufacturing toolkit
Addressing glass particulates in injectable drug formulations
Glass particles are a frequent contaminant risk when producing injectable drugs on high speed filling lines. Glassmaker Corning has studied the root causes and engineered a new glass product for use on existing equipment that significantly reduces that risk
Using ddPCR to accurately quantify AAV viral titre and integrity
Gene therapy is primed to become the next major development in medicine and bring relief to patients living with diseases ranging from haemophilia to Alzheimer’s disease, write Mark White, Associate Director of Biopharma Product Marketing, and Marwan Alsarraj, Biopharma Segment Manager, Bio-Rad
Host cell protein analysis: strategies to improve sensitivity and reproducibility
Given that the US FDA approved 25 new cellular and gene therapy products in 2022, gene-based vaccines and therapeutics have now entered the mainstream pharmaceutical industry. However, the rising interest in gene-based strategies puts pressure on manufacturers to demonstrate optimum efficacy and safety
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