At this year's CPHI & PMEC India, Romaco will be showcasing its complete processing portfolio for pharmaceutical solids.
This includes granulation, tableting and coating machinery.
The company's experts will also be on hand to discuss its primary, secondary and final packaging solutions suitable for a wide variety of pharmaceutical products.
At the event, Romaco will place a special focus on its fluid bed processors (Romaco Innojet), tablet presses (Romaco Kilian) and drum coaters (Romaco Tecpharm), which are all capable of dealing with a broad range of products.
These solutions have also been optimised to cut manufacturing costs, shorten processing times and save energy.
Users and prospects will also have the chance to develop and test their products on Romaco's laboratory equipment at the company's new Customer Experience Centre in Hyderabad.
Here, they will be able to gather expert advice and support for scale-up trials, as well as process optimisation and troubleshooting.
KTP 720X double-sided rotary press
Romaco Kilian’s KTP 720X double-sided rotary press is now also available with a segment turret for up to 30% more performance. The configuration with five segments and up to 115 punch stations enables a maximum output of up to 1,380,000 tablets per hour.
What’s more, the segment turret also significantly reduces retooling and cleaning times. The individual segments have product-specific punch holes and are easy to remove for cleaning; the time-consuming removal of the dies is no longer necessary.
Thanks to the hermetic separation between the compaction and service areas, no tablet dust gets into the machine area during production, so that far less effort is required for cleaning. The number of product-contacted parts has been systematically reduced at the same time. Patented punch bellows protect the tablets reliably from contamination with lubricants.
The high-speed press can be used to manufacture both mono-layer and bi-layer tablets, whereby the temperature in the compaction area is kept at a constant level below 30 °C. This is achieved, for example, through low-friction pressure rollers, pins and bearings as well as efficient cooling of the V-ring seals and drives. The technology is consequently ideal for processing temperature sensitive medications such as Metformin or Ibuprofen. All in all, the double-sided rotary press convinces with its excellent TCO (total cost of ownership) and OEE (overall equipment effectiveness).
TPR 25 Pilot mobile tablet coater from Romaco Tecpharm
The TPR 25 Pilot mobile tablet coater is an extremely compact pilot-scale unit for simple plug & play commissioning. For this purpose, all inlet and exhaust airflow systems required for the coating process have been integrated into the machine. As a modern all-in-one solution, its applications cover everything from development activities and scale-ups to the production of very small batches.
The pilot coater is designed for batches weighing between 1 and 25 kg, making it suitable for an extremely wide batch size range from 5 to 100%. The coating pan’s enormous flexibility is made possible by fully automated processes requiring no manual adjustments. The TPR 25 Pilot is equipped with a patented spray arm, which is controlled by a sonar system that automatically adjusts the distance between the spray gun and the tablet bed.
Thanks to the spray arm’s intelligence, the coater does not have to be stopped and opened to correct the spray distance while the process is running. In addition to this, the extendable spray arm has movable nozzles to ensure the ideal spray angle in any situation. The process air flowing through the tablet bed follows a precisely controlled path, which can be automatically adapted to the filling level in the drum with the aid of an exhaust flap that opens steplessly.
This results in remarkably accurate application of the coating suspension and ultra-efficient drying of the tablet bed. From a sustainability viewpoint, Romaco Tecpharm’s TPR 25 Pilot consequently impresses with significantly shorter processing times coupled with lower energy and spray liquid consumption.
VENTILUS Lab fluid bed processor from Romaco Innojet
Designed for laboratory-scale applications, the VENTILUS® Lab fluid bed processor from Romaco Innojet is used for granulating, drying and coating particles of any size from 10 μm to 2 mm.
This multipurpose lab unit is intended for batch sizes from 0.7 to 7.0 L. With its innovative process air distribution system inside the cylindrical product container, the VENTILUS Lab shortens batch processing times by up to 25%, as the required power can be used far more efficiently. The process air is introduced through the circular ORBITER booster, ensuring homogeneous flow conditions and extremely gentle intermixing of the batch.
In combination with a central bottom spray nozzle, the ORBITER booster plate forms a unique functional unit enabling much simpler scale-up processes. When it comes to nozzle technology, users can choose between the tried-and-tested ROTOJET spray nozzle and the new FLEXIJET, which was specifically developed for granulation processes and is not only very easy to handle but also quick to clean.
The patented fluid bed components invented by Dr Herbert Hüttlin lie behind the remarkably accurate application of the spray liquid with a precisely defined droplet size. With controlled release formulations, for instance, the modified release profiles are achieved using 10 to 15 percent less material.
This targeted reduction in spray liquid usage also means less power consumption, so that the VENTILUS Lab results in substantially fewer carbon dioxide emissions from fluid bed processes. Furthermore, the rotating SEPAJET® filter system minimises general product loss by returning particles retained by the filter to the process rather than discharging them.
On show from November 26 to 28, 2024 at CPHI & PMEC India (Delhi NCR, Greater Noida, India Expo Centre, Hall 10, Stand C03).
