Solve sample solubility issues in liquid chromatography purification

Published: 6-Mar-2009

Lack of column capacity is one problem that can occur when there are solubility limitations with certain samples that researchers need to purify. The normal solution is to simply increase the number of injections, which increases the time and the cost of the project prorate.

Lack of column capacity is one problem that can occur when there are solubility limitations with certain samples that researchers need to purify. The normal solution is to simply increase the number of injections, which increases the time and the cost of the project prorate.

Now there is a solution from Dynamic Extractions – a compact HPCCC instrument that is compatible with existing LC systems and allows the use of a liquid stationary phase to solve the solubility problem.

This provides both liquid mobile and stationary phases and sample injection options have are tripled. Users can load either in the mobile or stationary phase or a mixture of the two – whichever combination allows the highest loading per injection.

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