Chiral active pharmaceutical ingredients (APIs) play an important role in the pharmaceutical and fine chemical industry. The global demand for these chemicals is increasing and consequently, there is a need for more efficient and sustainable methods for their production. The world is becoming more complex – as are the challenges it faces. Often experts from various fields have to co-operate to find innovative solutions and as a result, knowledge management is increasingly important for manufacturers in the pharmaceutical industry.
A good example of the very specific knowledge that can be shared to produce a new and better process is the reactivation of homogeneous chiral catalyst complexes after contact with water and reactions in liquid/liquid multi-phase systems.
Manufacturers of APIs face several challenges, including the increasingly stringent regulation of the market and the desire for more sustainable production. These circumstances require innovation and research into new approaches. Former scientists from Technische Universität Berlin and Max Planck Institute now form the development team of DexLeChem. This German spin-off from the Cluster of Excellence Unifying Concepts in Catalysis (UniCat) has developed a sustainable and economic method for the production of APIs.
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