Sample solubility dramatically impacts the amount of work a chromatographer can perform. When faced with solubility limitations the normal approach is to simply increase the number of injections, which pro-rata increases the time and the cost of the project.
Now there is a new solution - HPCCC instrumentation - allowing you to use a liquid stationary phase rather than solid. With both mobile and stationary phases now liquids your options to solubilise your samples have tripled. Your can solubilised in the individual mobile or stationary phases or a mixture of the two, whichever combination that allows the highest sample loading.
To find out more contact Dynamic Extractions.