Automated visual inspection: reducing false rejects with intelligent bubble masking

Published: 16-Feb-2026
Manufacturing

This article explores how intelligent bubble masking in automated visual inspection systems can significantly reduce false rejects in biopharmaceutical manufacturing by accurately distinguishing harmless bubbles from harmful particles

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Many biopharmaceuticals are prone to air bubble formation. Camera inspection systems often struggle to distinguish harmless bubbles from harmful particles, leading them to incorrectly reject perfectly good products at the end of the manufacturing process.

Here, bubble masking algorithms act as a true game-changer, accurately distinguishing between the good and the bad. Even a small improvement can significantly improve overall production efficiency.

Syntegon Technology's Leoni Ransmann, Global Product Manager, Inspection Technology, and Jan Sende, Vision and CCIT Expert, report.

Bubble formation can occur in many liquid pharmaceutical and biopharmaceutical products and is more common than it might initially appear. 

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