Manufacturing effervescent dosage forms is often challenging
Beneo has introduced galenIQ 721, a filler-binder is designed to enable pharmaceutical and nutraceutical manufacturers to target consumers that have difficulty swallowing standard tablets. A non-hygroscopic, water-soluble and directly compressible excipient, the product also provides content uniformity and production efficiency for effervescent applications, the company says.
Effervescent powders and tablets offer a more convenient way to deliver medicines or dietary supplements. They dissolve upon contact with water to release carbon dioxide and create a drink. In addition, Beneo says, they can be used to formulate pharmaceuticals that are difficult to digest, that cause stomach or esophageal irritation or that rely on a rapid onset of action, such as analgesics.
Manufacturing effervescent dosage forms is often challenging, however. To produce highly stable tablets, a non-hygroscopic, direct compression filler-binder is needed. This ensures high content uniformity and facilitates production.
Dr Maj-Britt Cepok, Head of Business Development, Pharma, Beneo, comments: “Fizzy tablets are ideally suited to administer a wide range of light-, oxygen- and other sensitive active ingredients and those that require a large dose. In addition, effervescent preparations are more appealing to consumers than traditional dosage forms. galenIQ 721 helps manufacturers to tap into this market and enhance their development programs.”