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Market Reports
Super early bird tickets now on sale for Manufacturing Chemist Live 2020
Manufacturing Chemist Live will provide guidelines and regulations for delegates seeking solutions to optimise pharmaceutical production and safety in the manufacturing environment
Distributed control system reduces downtime for pharmaceutical manufacturer
In this case study, Rockwell Automation describes how Mallinckrodt Pharmaceuticals was able to streamline production and pinpoint potential bottlenecks by implementing a virtualised control system architecture
Flexibility through standardisation
The global pharmaceutical industry is going through a significant transformation, shifting from blockbuster drugs to personalised medicines based on biotechnology and genomics
There’s more than one way to produce pharmaceutical water
Bosch Packaging’s Susanne Handrick and Nils Ern examine the potential of cold membrane processes for the production of pharmaceutical water for injection
Winner of the Nobel Prize in Physiology or Medicine
William Kaelin Jr, Sir Peter Ratcliffe, and Gregg Semenza have won the Nobel Prize for Physiology or Medicine 2019 for their discoveries of how cells sense and adapt to oxygen availability
Medical cannabis made in Italy
Dr Fabio Di Francesco, a compounding pharmacist based in Rome, describes how cannabis is used in various dosage forms and the challenges ahead
Almac FAST: Continuous flow chemistry with assisted synthesis technology
Flow assisted synthesis technology (FAST) is a unique flow chemistry platform for continuous production of chemicals when batch-based processes fail to deliver the required quality of product
Peak identification by LC/MS: Automation versus analyst
High pressure liquid chromatography/mass spectrometry (LC/MS) is an important technique that facilitates the correct and accurate identification of impurities in pharmaceutical products and intermediates
Testing the limits of dosage production with continuous direct compression technology
GEA’s Dr James Holman, Head of New Development and Innovation, Pharma, discusses the process robustness and operational considerations of the company’s CDC 50 platform during a 120-hour trial run
Beximco Pharma: The Bangladeshi company connecting with the US
COO Rabbur Reza talks about the strategy behind approaching pharmaceutical manufacturing from an emerging market
Addressing the need for cost-effective vaccine manufacturing
Process intensification and integrated continuous bioprocessing are two approaches that can be used to achieve cost-effective, local production of high-quality biologic products. Tania Pereira-Chilima, Product Manager at Univercells, explains
Future market dynamics and opportunities in immuno-oncology
Long-term survival, tumour-agnostic effects and the potential for cure in a fraction of patients are key catalysts driving the explosion of research and recent approvals in IO. Dr Kevin Robinson recently caught up with SmartAnalyst’s Nidhi Dhingra and Jaideep V. Thottassery to delve a little deeper
A microfluidic approach to production of alginate beads for cell encapsulation
Gurinder Vinner, Material Scientist at Dolomite Microfluidics, discusses the benefits of continuous microfluidic production for the encapsulation of mammalian cells with no loss of viability
The case for single-use architecture in pharma
Billy Sisk, Life Sciences Industry Manager, EMEA, at Rockwell Automation recently contributed to the free downloadable e-book, the <i>Big Book of Biotech</i>, alongside input from GSK, Merck, ZeClinics and others. Here, for readers of <i>Manufacturing Chemist</i>, he picks up his topic of single-use facilities
Case Study: Phase I to commercial in 18 months
Gabor Heltovics, Druggability Technologies CEO, talks about using Quotient Sciences to progress and scale-up an improved pain relief drug formulation
Manufacturing misconceptions: The difficulties of tackling big data analysis
The advent of Industry 4.0 offers huge potential to explore new and exciting changes to the manufacturing floor, comments Dirk Ortloff, Department Manager, camLine
Guide to wash-in-place process in horizontal mixing systems
Modular solutions are proven to reliably fulfil any industry-specific requirements in the pharmaceutical, food, cosmetics, and chemical industries. Sebastian Steinkamp of Lödige provides a step-by-step guide to effective cleaning
Stainless steel products in contemporary bioprocessing
ASEPCO's Mark Embury on the shift from stainless steel to single-use systems in the pharmaceutical manufacturing sector
A rules-based approach to labelling and artwork management: Part I
Many organisations today are experiencing unprecedented demands from regulatory authorities and consumers alike for product labelling to be made clearer and more informative, says Graham Francis, Channel Marketing Manager, Kallik
A new approach to molecular imaging in cancer patients
A variety of different imaging approaches, spanning molecular to whole-body scans, have contributed greatly to our understanding of the conditions required for an effective anticancer immune response, reports Ian Wilson, CEO, ImaginAb
Unlocking R&D potential with equipment expertise
Worldwide, pharmaceutical manufacturers face a daunting challenge: that of reconciling ever-higher cost pressures with increased quality requirements
Taking a multifaceted approach to combatting superbugs
Paul Chapman, Partner at Marks & Clerk LLP, takes a look at research underway for testing a compound on Gram-negative bacteria known for being the most difficult to treat of all infections
Seal selection for pump optimisation
Process containment and reducing the risk of product contamination are key requisites for pharmaceutical production equipment. Yet the industry is notoriously averse to change when it comes to the selection of mechanical seals and seal materials, says John Smiddy, European Business Development and Technical Support Director for AESSEAL
Integrated tools for upstream process intensification: Part I
Changes to bioprocessing methodologies are driven by the need for increased speed, a lower cost of goods and greater flexibility, writes Gerben Zijlstra, Global Technology Consultant at Sartorius Stedim Biotech
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Trending Articles
How to avoid sticking and picking in the tableting industry
John Norman and Kevin Queensen of Natoli Engineering explain
Drug dose delivery development, manufacturing and commercialisation trends: part II
In the wake of patient-centricity in the pharmaceutical industry, drug delivery technologies have emerged as a central driver of therapeutic and patient success. Dr Kevin Robinson went online with Manuel Leal, Business Development Director, Idifarma, Steve Rode, Manager Business Development, Capsules and Health Ingredients, Lonza, and John Ross, President, Mayne Pharma US/Metrics Contract Services, to find out more
How to proactively address EU HTAR implementation challenges before 2025
Data landscape challenges within the European Union (EU) have historically been driven by the different laws, processes and regulatory standards of its 27 member states (MS). As a result, drug therapeutics and health technology developers have faced the challenge of duplication of assessment efforts
Highly potent formulation development in oncology
Formulation development is a dynamic and experimental process. However, certain challenges are presented to CDMOs that add a layer of unnecessary pressure to the development process — some of which are avoidable. Louise Carpenter from PCI Pharma Services discusses
Reading and understanding vendor-supplied tablet drawings
Understanding the tablet drawings supplied by tooling vendors is a meaningful way to learn more about your product, reports John Norman, Technical Service Representative, Natoli Engineering Company
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