Market Reports

Future market dynamics and opportunities in immuno-oncology

Long-term survival, tumour-agnostic effects and the potential for cure in a fraction of patients are key catalysts driving the explosion of research and recent approvals in IO. Dr Kevin Robinson recently caught up with SmartAnalyst’s Nidhi Dhingra and Jaideep V. Thottassery to delve a little deeper

A microfluidic approach to production of alginate beads for cell encapsulation

Gurinder Vinner, Material Scientist at Dolomite Microfluidics, discusses the benefits of continuous microfluidic production for the encapsulation of mammalian cells with no loss of viability

The case for single-use architecture in pharma

Billy Sisk, Life Sciences Industry Manager, EMEA, at Rockwell Automation recently contributed to the free downloadable e-book, the <i>Big Book of Biotech</i>, alongside input from GSK, Merck, ZeClinics and others. Here, for readers of <i>Manufacturing Chemist</i>, he picks up his topic of single-use facilities

Case Study: Phase I to commercial in 18 months

Gabor Heltovics, Druggability Technologies CEO, talks about using Quotient Sciences to progress and scale-up an improved pain relief drug formulation

Manufacturing misconceptions: The difficulties of tackling big data analysis

The advent of Industry 4.0 offers huge potential to explore new and exciting changes to the manufacturing floor, comments Dirk Ortloff, Department Manager, camLine

Guide to wash-in-place process in horizontal mixing systems

Modular solutions are proven to reliably fulfil any industry-specific requirements in the pharmaceutical, food, cosmetics, and chemical industries. Sebastian Steinkamp of Lödige provides a step-by-step guide to effective cleaning

Stainless steel products in contemporary bioprocessing

ASEPCO's Mark Embury on the shift from stainless steel to single-use systems in the pharmaceutical manufacturing sector

A rules-based approach to labelling and artwork management: Part I

Many organisations today are experiencing unprecedented demands from regulatory authorities and consumers alike for product labelling to be made clearer and more informative, says Graham Francis, Channel Marketing Manager, Kallik

A new approach to molecular imaging in cancer patients

A variety of different imaging approaches, spanning molecular to whole-body scans, have contributed greatly to our understanding of the conditions required for an effective anticancer immune response, reports Ian Wilson, CEO, ImaginAb

Unlocking R&D potential with equipment expertise

Worldwide, pharmaceutical manufacturers face a daunting challenge: that of reconciling ever-higher cost pressures with increased quality requirements

Taking a multifaceted approach to combatting superbugs

Paul Chapman, Partner at Marks & Clerk LLP, takes a look at research underway for testing a compound on Gram-negative bacteria known for being the most difficult to treat of all infections

Seal selection for pump optimisation

Process containment and reducing the risk of product contamination are key requisites for pharmaceutical production equipment. Yet the industry is notoriously averse to change when it comes to the selection of mechanical seals and seal materials, says John Smiddy, European Business Development and Technical Support Director for AESSEAL

Integrated tools for upstream process intensification: Part I

Changes to bioprocessing methodologies are driven by the need for increased speed, a lower cost of goods and greater flexibility, writes Gerben Zijlstra, Global Technology Consultant at Sartorius Stedim Biotech

The future of supply chain management in pharmaceuticals

Global regulations and local legislation have made serialisation in the pharmaceutical industry standard practice. And, although serialisation is now commonplace, the supply chain is still beset with potential issues such as counterfeit products, says Andreas Bechthold, General Manager, Mettler-Toledo

Recombinant cultures for superior enzyme output

A non-GMP enzyme manufacturing process at Porton Biopharma has been converted from native production to recombinant using bioinformatics and next-gen sequencing. David Gervais, Head of Product and Fermentation Development, explains the method

Preparing for the paradigm shift in bioprocessing

While upstream titers have improved dramatically over the last decade, downstream processing has remained relatively unchanged. Now is the time to push efficiencies, and Renaud Jacquemart explains how the Natrix technology could offer a helping hand

Advances in biopharmaceutical manufacturing control strategies

The inherent complexity of biopharmaceutical products presents an ongoing challenge for manufacturers, particularly in the drive towards continuous manufacturing operations, writes Dr Richard Moseley, Chief Technologist, Microsaic Systems

Harnessing dark data in early stage drug development

A 1966, anticipating the impact of rapid advances in computing, a <i>Time</i> magazine article hypothesised: “By 2000, the machines will be producing so much that everyone in the US will, in effect, be independently wealthy. How to use leisure time will be a major problem.” Graeme Dennis, Commercial Director of Preclinical Pharma, IDBS, reports

Single-pass tangential flow filtration: A versatile approach to streamlining biomanufacturing

Current trends in the biopharmaceutical industry are driving the implementation of high capacity processes that are capable of reducing costs and equipment footprint without sacrificing manufacturing efficiency and product quality

Review: Cannabis Europa 2019

Scientists, businesspeople and politicians backing the regulation of medical and recreational cannabis have taken the stage of Southbank Centre this week to discuss research and business opportunities

Register now: Lab Innovations celebrates Year of the Periodic Table

Event in Birmingham will feature 35 hours of educational CPD-accredited seminars and the Cleanroom Hub in partnership with <em><a href='http://www.cleanroomtechnology.com'>Cleanroom Technology</a></em> magazine

CMC strategies for the acceleration of commercial-ready ADC manufacturing

The potential for antibody-drug conjugate (ADC) programmes to accelerate from early to late stage clinical development highlights the need to establish commercial launch-ready manufacturing early and efficiently, reports Courtney Morgret, Senior Scientist, Manufacturing Sciences, AbbVie

Video: Silverson manufactures 19ft Duplex Disintegrator mixer in-house

Multimedia showcases the largest batch mixer in the Silverson range as it comes to life

ECH Medical to open the UK's first standalone cannabis clinic

Company has also facilitated the import of the UK's first bulk shipment of cannabis-based medicine

Trending Articles

  1. How iPSCs can bridge the translational gap in neuroscience Affecting more than one in three people, neurological disorders have a vast impact on global health while exacting a tremendous cost, reports Dr Max Mirza, Vice President of Neuroscience Drug Discovery at Sygnature Discovery
  2. A natural remedy for brain metastasis Milk thistle extract might be a promising complementary treatment for cancer patients, reports Andrea Zangara, Scientific Marketing Manager, Euromed
  3. How to avoid sticking and picking in the tableting industry John Norman and Kevin Queensen of Natoli Engineering explain
  4. Peak identification by LC/MS: Automation versus analyst High pressure liquid chromatography/mass spectrometry (LC/MS) is an important technique that facilitates the correct and accurate identification of impurities in pharmaceutical products and intermediates
  5. Rare diseases: understanding the patient journey In the shadow of Rare Disease Day on 28 February 2019, Dr Kevin Robinson met with Zizi Imatorbhebhe, Senior Director of Strategic Development and Head of PAREXEL’s Rare Disease Center of Excellence (RDCE), to discuss the future of rare disease research

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