Wearable pumps and subcutaneous delivery: a new frontier in heart failure management

By Kevin Robinson | Published: 15-May-2026
Drug Delivery

Two recent developments are reshaping how drug delivery technology can move treatment out of the clinic and into patients’ everyday lives — with implications for both formulation science and device manufacturing

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Results from the SUBCUT HF II trial, presented at the European Society of Cardiology Heart Failure Congress 2026 in Barcelona, have demonstrated that wearable subcutaneous drug delivery can safely replace prolonged intravenous therapy for patients with worsening heart failure.

Led by researchers at the University of Glasgow, the study enrolled 172 patients across 20 UK hospitals, with participants on the device arm discharged from hospital an average of 5 days earlier than standard care (after approximately 2 days of inpatient monitoring rather than the typical 9–10).

At the centre of the innovation is a skin-friendly subcutaneous formulation of furosemide, paired with a wearable mini-pump developed by SQ Innovation Inc. 

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