Doyen technology improves transdermal device manufacture

German company Novosis AG has installed a converting and packaging line designed to improve production efficiency in the manufacture of transdermal devices.

The new system optimises the development and production of a variety of transdermal devices, as it is adaptable to manufacture products in different shapes and sizes with a minimum of downtime at changeover. A customised process efficiently minimises ladder waste of the drug. Automatic registration optimises the cut position, decreasing the number of patches rejected by the integrated quality control station.

The system uses Doyen's Transdermal Device Manufacturing and Four Side Seal Packaging technologies, converting up to 25 meters of PET/PE per minute. The transdermal patches are fed automatically onto Doyen's 4SS-400 four-side seal pouching machine to be hermetically sealed into peelable packs. An integrated quality control system detects and rejects splice, empty pouches and misplaced products.

Hubert Kaffl, process development at Novosis, said: "Doyen has provided us with a production line that is flexible enough to run tests on a varied range of transdermal devices. We are very impressed with the versatility and efficiency of the machine.

"I am delighted to say that we have recently placed an order for a second machine."

Doyen is based in Norfolk, UK.