The expansion follows Charles River's acquisition of Cognate BioServices and Cobra Biologics, a pioneering plasmid DNA, viral vector, and cell therapy CDMO in March 2021
Charles River Laboratories International has announced the opening of its High Quality (HQ) Plasmid DNA Centre of Excellence at Bruntwood SciTech's Alderley Park in Cheshire, United Kingdom.
The expansion follows Charles River's acquisition of Cognate BioServices and Cobra Biologics, a pioneering plasmid DNA, viral vector, and cell therapy contract development and manufacturing organisation (CDMO), in March 2021, and will support the growing needs of customers. With turnaround times from 48 hours for off-the-shelf products to custom HQ plasmid DNA manufacturing services within five weeks or more, the expansion both accelerates and safeguards future supply for cell and gene therapy developers.
The new 16,000 sqft facility is part of Charles River's mission to expand its end-to-end capabilities in cell and gene therapy development, adding to a growing global network that will help fast-track the process of bringing therapies to market.
Specifically, the new site, and the addition of three new manufacturing streams, will enable the company to quadruple its HQ plasmid DNA capacity to address global supply shortages and support therapeutic developers through rapid access to material.
Additional manufacturing slots are available from September 2022, with immediate project initiation.
“Our team has had decades of success developing, producing, and reliably delivering plasmid DNA, which ensures customers are in safe hands. Alderley Park is an impressive life sciences hub with a thriving ecosystem and Charles River is excited to be a part of the community,” said Nick Smith, Site Director of Alderley Park for Charles River.