The percentage of new drug candidates that are highly potent is rising, driving the need for additional manufacturing capacity for highly potent compounds. However, producing these challenging molecules is a complex process. Specialised facilities, equipment and highly skilled personnel are required.
Approximately 25% of new chemical entities are considered to be potent, which can largely be attributed to the fact that about one-third of all drug candidates are oncology treatments. The largest percentage of HPAPIs are used in the formation of anti-cancer drugs.
Advances in manufacturing and containment technologies and investments by manufacturers are facilitating the expansion of the market. Interest in targeted therapies with reduced side-effects, most notably antibody-drug conjugates (ADCs), is another key driver of demand growth for HPAPIs.
The increasing focus on highly potent active pharmaceutical ingredients (HPAPIs) in pharmaceutical development pipelines has led to a growing requirement for the capability to safely handle and contain these hazardous ingredients.
Manufacturing Chemist Live is designed to meet the needs of pioneers, experts and decision makers working in the pharma manufacturing sector. Industry leaders are invited to join the inaugural conference to highlight the latest in HPAPI processing and handling from regulations and compliance to the latest in production optimisation.
The 2020 conference will feature recent breakthroughs and challenges entirely relevant to those striving to optimise production, processing and efficiency in HPAPI handling.
Topics to be included
- HPAPI Processing and handling
- Raw materials handling
- Technology
- Facility design & build
- Containment
- Scale-up & tech transfer
- Process optimisation
- Packaging & drug delivery
- The future
Lead the way towards manufacturing excellence
For consideration, please send us your non-commercial presentation title and brief abstract by 31 August 2019.
For more information about the conference, visit the event's official website here.
Any other ideas? If you would like to address a particular issue, topic or query at the event, please contact Ali Badr on +44(0)207 193 6654 or email events@hpcimedia.com.
