SAFC Ex-Cell Antifoam increases cell culture consistency

Published: 19-Nov-2009

SAFC Biosciences has introduced Ex-Cell Antifoam, a non-animal origin solution that enhances foam control in cell culture bioreactors to increase consistency, efficiency and stability in cell culture manufacturing.


SAFC Biosciences has introduced Ex-Cell Antifoam, a non-animal origin solution that enhances foam control in cell culture bioreactors to increase consistency, efficiency and stability in cell culture manufacturing.

The Ex-Cell Antifoam is formulated from a 30% simethicone emulsion and validated by a simethicone quantification assay that confirms lot-specific concentration.

This USP grade non-ionic emulsion is used by the pharmaceutical and veterinary biological industries to assist in the control of cell culture foaming in bioreactors. Through formulation optimisation, use of a quantitative assay and understanding the non-specific binding of simethicone, SAFC Biosciences says it can report the actual simethicone concentration of the gamma irradiated finished material, producing a stable end product, thus ensuring product consistency, predictability and desired performance with at least a 13-month shelf life.

Ex-Cell Antifoam is available in one- and five-litre bags.

  • Companies:
  • Merck Group
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